5. Acquired Hemophilia

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Acquired Hemophilia

To the Editor, I would like to highlight 3 of our patients, a 14-year-old boy and females of 4 and 41 years old [1,2] with acquired hemophilia B seen at İhsan Doğramacı Children’s Hospital (previously Hacettepe) between 1963 and 1973 among 343 patients with hemophilia [3] on account of the case of acquired hemophilia A in a 78-year-old man who was successfully treated with a combined immunosupp...

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Acquired hemophilia.

Acquired hemophilia is a very rare disease characterized by the presence of an autoantibody (mainly IgG) to factor VIII, with a clinical presentation resembling hemophilia A. It is associated with various autoimmune or dermatologic diseases, pregnancy, cancer, or drug ingestion, but in almost 50% of patients no underlying disorder is found. The treatment of acquired hemophilia is particularly c...

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Acquired Hemophilia A

Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an auto antibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs [1]. Acquired hemophilia is significantly rarer than the inherited form, affecting around 2 per mil...

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Acquired Hemophilia in Pediatric Population.

The development of acquired inhibitors against the factor VIII protein in childhood period, is a very rare disorder in nonhemophiliac persons but may be clinically important condition due to potential serious bleedings. We have investigated acquired hemophilia development frequency in children with potential high risk groups. Totally 483 nonhemophiliac children including healthy controls were e...

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The problem of acquired hemophilia.

modern leukemia and lymphoma sequencing standards, is an improvement in signal-to-noise ratio for Hodgkin lymphoma given the incredible rarity of the Reed-Sternberg cell in its background nest of inflammatory infiltrate. Previous studies relying on laser capture microdissection could also increase the signal-to-noise ratio, but at the cost of time, effort, and still-low cell numbers. This work ...

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ژورنال

عنوان ژورنال: Nihon Naika Gakkai Zasshi

سال: 2014

ISSN: 0021-5384,1883-2083

DOI: 10.2169/naika.103.1622